Endocan a novel circulating proteoglycan

As most proteoglycans exert their biological activities in the pericellular region, circulating Endocan has appeared since its discovery as an atypical dermatan sulfate proteoglycan, with distinctive structural and functional properties.

Results: The study Endocan: A novel circulating proteoglycan. Indian J 7 Jan 2016 Endocan, a proteoglycan whose core protein is glycanated by a single A novel panel of biomarkers in distinction of small well-differentiated Endocan in cancers: a lesson from a circulating dermatan sulfate proteoglycan. Current studies on endothelial biomarkers are focusing on circulating endothelial Structurally endocan is a cystein-rich proteoglycan carrying a single chain of The literature analysis has also revealed endocan test as a promising novel 20 Apr 2015 Endocan levels at day 0 in patients with bacteremia were higher than those without Endocan is a proteoglycan that can be detected in human blood and is (2001) Endocan is a novel chondroitin sulfate/dermatan sulfate Endocan: A novel circulating proteoglycan Endocan is a novel endothelium derived soluble dermatan sulfate proteoglycan. It has the property of binding to a wide range of bioactive molecules associated with cellular signaling and adhesion and thus regulating proliferation, differentiation, migration, and adhesion of different cell … Endocan: A novel circulating proteoglycan | Request PDF Endocan is a novel endothelium derived soluble dermatan sulfate proteoglycan. It has the property of binding to a wide range of bioactive molecules associated with cellular signaling and adhesion Endocan: a novel circulating proteoglycan. Endocan is a novel endothelium derived soluble dermatan sulfate proteoglycan.

In this study, Endocan was taken as a novel tumor marker, which has been found in many cancers related to cancer cell proliferation, neoangiogenesis, etc.

Endocan regulates HGF/SF-mediated mitogenic activity and may support the function of HGF/SF not only in embryogenesis and tissue repair after injury but also in tumor progression. Prediction and identification of novel HLA-A*0201 ... Endocan is a soluble proteoglycan of 50 kDa, consisting of a mature polypeptide of 165 amino acids and a single dermatan sulfate chain . Endocan was originally described as being secreted by human umbilical vein endothelial cells (HUVECs) .

Endocan a novel circulating proteoglycan

Because this proteoglycan is speciﬁcally secreted by endothelial cells, the name proposed was “endocan.”2 Endocan is secreted by vascular endothelial cells in the skin, kidney, gastrointestinal tract, lungs, liver, brain, lymph nodes, heart, and thyroid gland.3 Normally, endocan is proposed to have a …

Endocan is a novel endothelium derived soluble dermatan sulfate proteoglycan. It has the property of binding to a wide range of bioactive molecules associated with cellular signaling and adhesion and thus regulating proliferation, differentiation, migration, and adhesion of different cell … Endocan: A novel circulating proteoglycan Kali A, Shetty ... Endocan is a novel endothelium derived soluble dermatan sulfate proteoglycan. It has the property of binding to a wide range of bioactive molecules associated with cellular signaling and adhesion and thus regulating proliferation, differentiation, migration, and adhesion of different cell … Endocan, Novel Potential Biomarker for Systemic Sclerosis ...

Endocan can be detected in the circulation and is an indicator of angiogenesis and endothelial cell activation .

Citation Endocan is a novel chondroitin sulfate/dermatan sulfate proteoglycan that promotes hepatocyte growth factor/scatter factor mitogenic activity. 2001, 276 (51):48341-9 J. Biol. Chem. [Full text] Endocan and the respiratory system: a review ... Delehedde M, Devenyns L, Maurage CA, Vivès RR. Endocan in cancers: a lesson from a circulating dermatan sulfate proteoglycan. Int J Cell Biol.

It is encoded by the esm1 gene, which is mainly expressed in the endothelial cells in human lung and kidney tissues. Endocan or endothelial cell specific molecule-1 (ESM-1): A ... Jan 01, 2006 · Read "Endocan or endothelial cell specific molecule-1 (ESM-1): A potential novel endothelial cell marker and a new target for cancer therapy, Biochimica et Biophysica Acta - Reviews on Cancer" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Letter to the Editor Highlight on Mouse Endocan To the Editor: There are now emerging data involving the endothelial cell– derived human endocan as a key actor of the tumor progression.

Background: Endocan, a novel protein involved in inflammation and endothelial dysfunction, has been suggested to be related to preeclampsia, although the results of previous studies were not consistent. The aim of the study was to evaluate the potential difference of circulating endocan in women with preeclampsia and those with Increase of circulating endocan over sepsis ... - SpringerLink Apr 28, 2017 · Changes of circulating cytokines do not mediate worsening of the critically ill patients. Instead endocan and Ang2 are increased and this may be interpreted as a key-playing role in the pathogenesis of ARDS and septic shock. Any increase of endocan is a … Endocan: A new marker for cancer and a target for cancer ...

Circulating Endocan Is a Novel Chondroitin Sulfate/Dermatan Sulfate ... Endocan Is a Novel Chondroitin Sulfate/Dermatan Sulfate Proteoglycan That Promotes Hepatocyte Growth Factor/Scatter Factor Mitogenic Activity Endocan Is a Novel Chondroitin Sulfate/Dermatan Sulfate ... Overall, our results demonstrate that endocan is a novel soluble dermatan sulfate proteoglycan produced by endothelial cells.

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